SMAD1/5 signaling in osteoclasts regulates bone formation via coupling factors
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چکیده
منابع مشابه
Signaling and Actin Ring Formation in Mature Osteoclasts via Suppression of the Src Signaling Pathway
Background: Caldecrin is a serum calcium-decreasing factor and inhibits osteoclast differentiation. Results: Caldecrin inhibits RANKL-stimulated Ca 2+ entry, sealing actin ring formation and bone resorption of mature osteoclasts in a c-Src-dependent manner. Conclusion: Caldecrin is a negative regulator of RANKL-mediated osteoclast function. Significance: Caldecrin contributes to the understandi...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0203404